EAF1-AS1

Across TCGA pan-cancer cohorts, EAF1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of EAF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where EAF1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types EAF1-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LIHC, and BLCA are the cancer types where EAF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EAF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.097	<.001	8	view →
LIHC	All	All	+0.077	<.001	8	view →
BLCA	All	All	+0.076	.019	6	view →
BRCA	All	II,III,IV	+0.082	.008	4	view →
COAD	All	All	+0.046	.006	4	view →
LUSC	Female	II,III,IV	−0.092	.036	3	view →
KIRP	Female	All	+0.113	.003	2	view →
PRAD	All	All	+0.059	.005	2	view →
LUAD	Female	II,III,IV	−0.151	.040	1	view →
KIRC	All	All	+0.022	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

EAF1-AS1–THCA

Open the THCA breakdown →