E2F2

Across TCGA patient cohorts, E2F2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,689 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible E2F2-associated proteins across cancer lineages are RPL12_S38, RRM2, and SMC2. Each is linked with E2F2 in more than 9 cancer types. Because this analysis shows association rather than direction, both E2F2-to-partner and partner-to-E2F2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, E2F2 versus RPL12_S38 in LUAD, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (E2F2→partner) and Y-score (partner→E2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL12_S38 →	+1.201	+0.971	<.001	<.001	3	10
LUAD	RRM2 →	+1.015	+0.948	<.001	<.001	3	10
GBM	SMC2 →	+0.778	+1.186	<.001	<.001	3	10
GBM	SMC4 →	+0.731	+1.137	<.001	<.001	3	10
UCEC	POLD1 →	+0.385	+0.814	<.001	<.001	3	10
OV	FEN1 →	+0.580	+1.102	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,689 associations by consensus.

E2F2 vs RPL12_S38 — LUAD

Explore this scatter interactively →