Across TCGA cell cohorts, DZIP3 mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DZIP3-associated genes across cancer lineages are DYDC1, ADAM2, and RPL3. Each is linked with DZIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DZIP3-to-partner and partner-to-DZIP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP3→partner) and Y-score (partner→DZIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DYDC1 →	+0.395	+4.276	<.001	.007	3	2
CNS	ADAM2 →	+0.027	+4.169	<.001	.008	3	2
LARGE_INTESTINE	RPL3 →	+0.591	+3.087	.001	.006	3	2
LARGE_INTESTINE	LCE1F →	+0.082	+3.192	<.001	.002	3	2
LARGE_INTESTINE	NOA1 →	+0.540	+3.212	.005	.006	3	2
SKIN	KRTAP5-4 →	+0.041	+3.240	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

Exploration

DZIP3 survival (RNA) · tumor vs normal (RNA) · all DZIP3 data types