DYTN

Across TCGA cell cohorts, DYTN RNA expression is significantly associated with the go_rna of many other GO terms, with 560 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYTN-associated GO terms across cancer lineages are Negative regulation of interleukin-1 production, Regulation of presynapse organization, and Regulation of voltage-gated calcium channel activity. Each is linked with DYTN in more than 2 cancer types. Because this analysis shows association rather than direction, both DYTN-to-partner and partner-to-DYTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of interleukin-1 production grouped by DYTN-low versus DYTN-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYTN→partner) and Y-score (partner→DYTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of interleukin-1 production →	+0.084	+0.280	<.001	.003	3	3
BLOOD_Leukemia	Regulation of presynapse organization →	+0.111	+0.302	<.001	.001	3	2
KIDNEY	Regulation of voltage-gated calcium channel activity →	-0.129	-0.004	.008	.009	3	2
KIDNEY	Cellular response to growth hormone stimulus →	+0.170	+0.004	<.001	.009	3	2
BLOOD_Leukemia	Positive regulation of inflammasome-mediated signaling pathway →	+0.054	+0.483	<.001	.004	3	2
BLOOD_Leukemia	Neurotransmitter uptake →	+0.122	+0.294	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 560 associations by consensus.

Negative regulation of interleukin-1 production by DYTN expression — BLOOD_Leukemia

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