DYTN

Across TCGA pan-cancer cohorts, DYTN RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated DYTN data layer compared with 6 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher DYTN RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DYTN expression acts as an unfavorable survival marker, although some lineages such as PCPG and ESCA show a favorable association.

SCLC, CHOL, and CESC are the cancer types where DYTN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Tertile	II,III,IV	0.164	0.819	<.001	54	view →
CHOL	DFS	Tertile	II,III,IV	0.032	0.477	<.001	54	view →
CESC	DFS	Tertile	All	0.683	0.840	<.001	48	view →
UCEC	DFS	Tertile	All	0.844	0.921	.001	38	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	36	view →
LUSC	OS	Median	III,IV	0.474	0.750	.003	33	view →
KIRC	DFS	Quartile	II,III,IV	0.574	0.716	.008	27	view →
KICH	DFS	Quartile	III,IV	0.032	0.795	.013	18	view →
THCA	OS	Tertile	All	0.948	0.987	.016	18	view →
TGCT	OS	Tertile	II,III,IV	0.795	1.000	.039	18	view →
LUAD	OS	Tertile	III,IV	0.275	0.673	.034	18	view →
SKCM	DFS	Tertile	II,III,IV	0.345	0.607	.013	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

DYTN–SCLC (OS)

Open the SCLC breakdown →