DYTN

Across TCGA cell cohorts, DYTN mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DYTN-associated genes across cancer lineages are XAGE3, MROH9, and TECTB. Each is linked with DYTN in more than 1 cancer types. Because this analysis shows association rather than direction, both DYTN-to-partner and partner-to-DYTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE3 grouped by DYTN-low versus DYTN-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYTN→partner) and Y-score (partner→DYTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	XAGE3 →	+0.163	+4.906	<.001	.006	3	1
LUNG_SCLC	MROH9 →	+0.199	+3.523	.001	.008	3	1
LUNG_SCLC	TECTB →	+0.070	+3.523	<.001	.008	3	1
LUNG_SCLC	TMEM82 →	+0.113	+3.523	<.001	.008	3	1
LUNG_SCLC	OR6F1 →	+0.061	+3.817	<.001	.004	3	1
LUNG_SCLC	GSTA3 →	+0.077	+3.523	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

XAGE3 by DYTN expression — OESOPHAGUS

Explore this box plot interactively →