DYTN

Across TCGA cell cohorts, DYTN mutation is significantly associated with the mutation status of many other genes, with 2,431 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DYTN-associated genes across cancer lineages are NADSYN1, RP1, and VEPH1. Each is linked with DYTN in more than 3 cancer types. Because this analysis shows association rather than direction, both DYTN-to-partner and partner-to-DYTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADSYN1 grouped by DYTN-low versus DYTN-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYTN→partner) and Y-score (partner→DYTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NADSYN1 →	+4.894	+4.894	.004	.004	1	4
LUNG_NSCLC_LUAD	RP1 →	+2.754	+4.189	.008	.008	1	4
BLOOD_Lymphoma	VEPH1 →	+5.014	+5.584	.003	.003	1	4
BLOOD_Leukemia	BTBD11 →	+3.309	+4.794	.002	.002	1	4
BLOOD_Lymphoma	PRTG →	+4.429	+5.247	.005	.005	1	3
LARGE_INTESTINE	CNTNAP5 →	+1.799	+3.769	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,431 associations by consensus.

NADSYN1 by DYTN expression — BLOOD_Leukemia

Explore this box plot interactively →