DYRK3-AS1

Across TCGA pan-cancer cohorts, DYRK3-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DYRK3-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher DYRK3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DYRK3-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and HNSC show a favorable association.

KIRP, MESO, and SKCM are the cancer types where DYRK3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.567	0.791	<.001	95	view →
MESO	DFS	Median	II,III,IV	0.513	0.296	.002	51	view →
SKCM	OS	Median	All	0.734	0.830	<.001	48	view →
LGG	OS	Median	All	0.746	0.870	<.001	48	view →
KIRC	OS	Median	All	0.761	0.846	.008	36	view →
HNSC	DFS	Quartile	IV	0.481	0.288	.005	33	view →
THCA	OS	Median	All	0.885	0.981	.003	26	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	24	view →
ACC	DFS	Quartile	All	0.625	0.945	.002	24	view →
UCS	DFS	Tertile	II,III,IV	0.555	0.226	.020	22	view →
LIHC	OS	Quartile	All	0.554	0.754	.007	19	view →
SARC	DFS	Quartile	All	0.396	0.678	.006	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DYRK3-AS1–KIRP (OS)

Open the KIRP breakdown →