DYRK2

Across TCGA cell cohorts, DYRK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,917 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYRK2-associated GO terms across cancer lineages are Oocyte growth, Response to dehydroepiandrosterone, and Negative regulation of calcineurin-NFAT signaling cascade. Each is linked with DYRK2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DYRK2-to-partner and partner-to-DYRK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by DYRK2-low versus DYRK2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK2→partner) and Y-score (partner→DYRK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Oocyte growth →	+0.126	+0.774	<.001	<.001	3	12
BONE	Response to dehydroepiandrosterone →	+0.162	+1.136	<.001	<.001	3	12
KIDNEY	Negative regulation of calcineurin-NFAT signaling cascade →	+0.195	+1.355	.003	<.001	3	12
KIDNEY	Negative regulation of calcineurin-mediated signaling →	+0.195	+1.355	.003	<.001	3	12
KIDNEY	Insulin-like growth factor receptor signaling pathway →	+0.096	+1.124	.005	.008	2	13
OVARY	Cellular response to insulin stimulus →	+0.048	+1.109	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,917 associations by consensus.

Oocyte growth by DYRK2 expression — BLOOD_Lymphoma

Explore this box plot interactively →