DYNLL2

Across TCGA patient cohorts, DYNLL2 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNLL2-associated genes across cancer lineages are RNU6-643P, RN7SL495P, and AQP7P3. Each is linked with DYNLL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYNLL2-to-partner and partner-to-DYNLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-643P grouped by DYNLL2-low versus DYNLL2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLL2→partner) and Y-score (partner→DYNLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-643P →	+0.434	+7.930	<.001	.008	3	2
UCEC	RN7SL495P →	+0.135	+4.335	.004	.007	3	2
UCEC	AQP7P3 →	+0.030	+4.582	.002	.005	3	1
UCEC	SEPTIN14P19 →	+0.039	+5.245	<.001	.002	3	1
UCEC	OR5J1P →	+0.133	+3.418	<.001	.009	3	1
UCEC	H2AP →	+0.209	+3.525	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

RNU6-643P by DYNLL2 expression — LUAD

Explore this box plot interactively →