DYNC1LI1

Across TCGA patient cohorts, DYNC1LI1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,521 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC1LI1-associated genes across cancer lineages are RAB5A, NGLY1, and CLASP2. Each is linked with DYNC1LI1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC1LI1-to-partner and partner-to-DYNC1LI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC1LI1 versus RAB5A in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC1LI1→partner) and Y-score (partner→DYNC1LI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB5A →	+0.527	+0.253	<.001	<.001	3	6
OV	NGLY1 →	+0.479	+0.367	<.001	<.001	3	6
GBM	CLASP2 →	+0.642	+0.240	<.001	<.001	3	6
LSCC	CNOT10 →	+0.486	+0.170	<.001	<.001	3	6
OV	FANCD2 →	+0.637	+0.282	.002	.002	3	5
COAD	CMTM6 →	+0.510	+0.166	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,521 associations by consensus.

DYNC1LI1 vs RAB5A — HNSC

Explore this scatter interactively →