Across TCGA patient cohorts, DXO protein abundance is significantly associated with the RNA expression of many other genes, with 4,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DXO-associated genes across cancer lineages are RPS10, PTPN7, and PLCG2. Each is linked with DXO in more than 3 cancer types. Because this analysis shows association rather than direction, both DXO-to-partner and partner-to-DXO results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DXO→partner) and Y-score (partner→DXO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS10 →	+0.738	+0.890	.004	.004	3	4
OV	PTPN7 →	-0.624	-0.447	.002	.002	3	3
OV	PLCG2 →	-0.819	-0.405	.004	.004	3	3
COAD	DAXX →	+0.643	+0.730	.002	<.001	3	3
COAD	WDR46 →	+0.637	+0.769	.001	.002	3	3
LSCC	NFKBIL1 →	+0.571	+0.432	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,026 associations by consensus.

Exploration

DXO survival (RNA) · tumor vs normal (RNA) · all DXO data types