Across TCGA patient cohorts, DXO protein abundance is significantly associated with the protein abundance of many other proteins, with 9,688 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DXO-associated proteins across cancer lineages are BUD13_S248, METTL14, and SRRM1_S646. Each is linked with DXO in more than 3 cancer types. Because this analysis shows association rather than direction, both DXO-to-partner and partner-to-DXO results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DXO→partner) and Y-score (partner→DXO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	BUD13_S248 →	+2.096	+1.943	.002	<.001	3	4
GBM	METTL14 →	+0.267	+0.430	<.001	<.001	3	3
CCRCC	SRRM1_S646 →	+0.987	+1.711	<.001	<.001	3	3
GBM	USP48 →	+0.382	+0.445	<.001	<.001	3	3
GBM	RBBP4 →	+0.314	+0.281	<.001	.005	3	3
CCRCC	ANP32B_T244 →	+2.878	+1.849	.001	<.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,688 associations by consensus.

Exploration

DXO survival (RNA) · tumor vs normal (RNA) · all DXO data types