Across TCGA patient cohorts, DXO mutation is significantly associated with the RNA expression of many other genes, with 425 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DXO-associated genes across cancer lineages are TIMM44, KATNBL1P4, and LINC02424. Each is linked with DXO in more than 1 cancer types. Because this analysis shows association rather than direction, both DXO-to-partner and partner-to-DXO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DXO→partner) and Y-score (partner→DXO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM44 →	+0.558	+3.617	<.001	.001	3	2
COAD	KATNBL1P4 →	+0.081	+6.409	.002	<.001	3	2
SKCM	LINC02424 →	+0.061	+5.097	<.001	.008	3	2
UCEC	MIR548D2 →	+0.325	+2.957	<.001	.009	3	2
UCEC	BNIP1 →	+0.412	+3.584	.003	.003	3	2
LIHC	MIR6827 →	+0.563	+6.149	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 425 associations by consensus.

Exploration

DXO survival (RNA) · tumor vs normal (RNA) · all DXO data types