Across TCGA cell cohorts, DXO mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DXO-associated genes across cancer lineages are GPR88 and SCT. Each is linked with DXO in more than 1 cancer types. Because this analysis shows association rather than direction, both DXO-to-partner and partner-to-DXO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DXO→partner) and Y-score (partner→DXO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GPR88 →	+0.011	+3.684	<.001	.006	3	1
LARGE_INTESTINE	SCT →	+0.206	+4.510	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

DXO survival (RNA) · tumor vs normal (RNA) · all DXO data types