DVL2

Across TCGA patient cohorts, DVL2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,845 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DVL2-associated genes across cancer lineages are ZNF286A, RPA1, and DHX33. Each is linked with DVL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DVL2-to-partner and partner-to-DVL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DVL2 versus ZNF286A in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DVL2→partner) and Y-score (partner→DVL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF286A →	+0.690	+0.296	<.001	<.001	3	7
LSCC	RPA1 →	+0.648	+0.382	<.001	<.001	3	6
OV	DHX33 →	+0.777	+0.373	<.001	<.001	3	6
UCEC	MYH10 →	+0.622	+0.196	.002	.002	3	5
LSCC	SNHG29 →	+0.630	+0.245	.002	<.001	3	5
OV	SHPK →	+0.356	+0.251	.003	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,845 associations by consensus.

DVL2 vs ZNF286A — LSCC

Explore this scatter interactively →