DUX4L8

Across TCGA patient cohorts, DUX4L8 RNA expression is significantly associated with the protein abundance of many other proteins, with 192 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DUX4L8-associated proteins across cancer lineages are RAB11FIP1_S529, MCTS1, and MTMR3_S647. Each is linked with DUX4L8 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUX4L8-to-partner and partner-to-DUX4L8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUX4L8 versus RAB11FIP1_S529 in UCEC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L8→partner) and Y-score (partner→DUX4L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAB11FIP1_S529 →	-0.672	-0.068	<.001	.009	3	1
CCRCC	MCTS1 →	+0.255	+0.015	<.001	.007	3	1
CCRCC	MTMR3_S647 →	-0.236	-0.016	.003	.009	3	1
CCRCC	MYBBP1A_S1267 →	+0.331	+0.015	.004	.007	3	1
CCRCC	ARFGEF3 →	+0.854	+0.015	<.001	.009	3	1
CCRCC	NNMT →	+1.286	+0.030	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

DUX4L8 vs RAB11FIP1_S529 — UCEC

Explore this scatter interactively →