DUX4L31

Across TCGA patient cohorts, DUX4L31 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,676 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DUX4L31-associated GO terms across cancer lineages are Liposaccharide metabolic process, Regulation of telomere maintenance in response to DNA damage, and Membrane lipid biosynthetic process. Each is linked with DUX4L31 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUX4L31-to-partner and partner-to-DUX4L31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Liposaccharide metabolic process grouped by DUX4L31-low versus DUX4L31-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L31→partner) and Y-score (partner→DUX4L31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Liposaccharide metabolic process →	+0.073	+0.037	<.001	<.001	3	4
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.097	+0.033	<.001	.002	3	4
STAD	Membrane lipid biosynthetic process →	+0.075	+0.019	<.001	.001	3	4
STAD	Response to actinomycin D →	+0.071	+0.021	<.001	<.001	3	4
STAD	Nucleoside triphosphate metabolic process →	+0.128	+0.020	<.001	.001	3	4
STAD	Fatty acid biosynthetic process →	+0.064	+0.027	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,676 associations by consensus.

Liposaccharide metabolic process by DUX4L31 expression — STAD

Explore this box plot interactively →