DUX4L27

Across TCGA patient cohorts, DUX4L27 RNA expression is significantly associated with the RNA expression of many other genes, with 13,887 significant associations in total. THYM shows the largest number of these associations.

The most reproducible DUX4L27-associated genes across cancer lineages are RNA5SP357, IPO5P1, and PRDM11. Each is linked with DUX4L27 in more than 27 cancer types. Because this analysis shows association rather than direction, both DUX4L27-to-partner and partner-to-DUX4L27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUX4L27 versus RNA5SP357 in LAML, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L27→partner) and Y-score (partner→DUX4L27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	RNA5SP357 →	+1.047	+1.005	<.001	<.001	3	28
ACC	IPO5P1 →	+1.138	+0.915	<.001	.002	3	23
THYM	PRDM11 →	+1.167	+1.213	<.001	<.001	3	23
ESCA	BEX4 →	+1.375	+0.457	<.001	<.001	2	23
THYM	ZNF606 →	+1.101	+1.341	<.001	<.001	3	22
UCS	MIR600HG →	+1.110	+1.419	.001	.007	1	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,887 associations by consensus.

DUX4L27 vs RNA5SP357 — LAML

Explore this scatter interactively →