DUX4L18

Across TCGA patient cohorts, DUX4L18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,381 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DUX4L18-associated GO terms across cancer lineages are Protein folding, Positive regulation of proteasomal protein catabolic process, and Regulation of response to oxidative stress. Each is linked with DUX4L18 in more than 4 cancer types. Because this analysis shows association rather than direction, both DUX4L18-to-partner and partner-to-DUX4L18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by DUX4L18-low versus DUX4L18-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L18→partner) and Y-score (partner→DUX4L18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein folding →	+0.081	+0.022	<.001	.002	3	5
STAD	Positive regulation of proteasomal protein catabolic process →	+0.082	+0.025	<.001	<.001	3	4
STAD	Regulation of response to oxidative stress →	+0.057	+0.041	<.001	.001	3	4
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.081	+0.027	<.001	<.001	3	4
STAD	Carbohydrate biosynthetic process →	+0.057	+0.025	<.001	<.001	3	4
STAD	Negative regulation of protein ubiquitination →	+0.081	+0.043	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,381 associations by consensus.

Protein folding by DUX4L18 expression — STAD

Explore this box plot interactively →