Across TCGA pan-cancer cohorts, DUTP7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DUTP7’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where DUTP7 RNA is repressed in tumor relative to normal tissue. In most cancer types DUTP7 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and KIRC are the cancer types where DUTP7 tumor–normal differential expression is most reproducible.