Q-omics provides the consensus-scored DUTP7 profile across patient tissues and cancer cell-line models. DUTP7 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, DUTP7 is differentially expressed in 2, with the highest sampling consensus in THCA. Additionally, DUTP7 RNA expression shows 9,888 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight UVM, THCA, and LAML as cancer lineages where DUTP7 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DUTP7 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DUTP7 survival associations across molecular data types. DUTP7 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DUTP7 RNA expression–survival associations across cancer types. High DUTP7 expression shows unfavorable associations in UVM, COAD, STAD, UCS, LIHC and LUSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for DUTP7 RNA expression.
This table summarizes DUTP7 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for DUTP7. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DUTP7 shows lower tumor expression in THCA and higher tumor expression in KIRC. The THCA box plot shows higher DUTP7 RNA expression in normal versus tumor tissue (log2 FC = −0.076, t-test p < 0.001).
This table shows molecular features associated with DUTP7 in patient tissues and cancer cell lines. In patient samples, DUTP7 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
