DUSP9

Across TCGA cell cohorts, DUSP9 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DUSP9-associated genes across cancer lineages are AMELX, UCMA, and UTF1. Each is linked with DUSP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP9-to-partner and partner-to-DUSP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMELX grouped by DUSP9-low versus DUSP9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP9→partner) and Y-score (partner→DUSP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AMELX →	+0.715	+3.745	<.001	.002	3	1
LARGE_INTESTINE	UCMA →	+0.014	+3.217	<.001	.006	3	1
LARGE_INTESTINE	UTF1 →	+0.017	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

AMELX by DUSP9 expression — LARGE_INTESTINE

Explore this box plot interactively →