DUSP9

Across TCGA pan-cancer cohorts, DUSP9 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated DUSP9 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DUSP9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DUSP9 expression acts as an unfavorable survival marker, although some lineages such as LGG and OV show a favorable association.

KIRC, UCEC, and COAD are the cancer types where DUSP9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.537	0.718	<.001	118	view →
UCEC	DFS	Median	All	0.787	0.884	<.001	74	view →
COAD	DFS	Quartile	IV	0.228	0.614	<.001	74	view →
KIRP	DFS	Tertile	All	0.611	0.795	<.001	72	view →
UVM	DFS	Median	III,IV	0.458	0.869	.001	72	view →
MESO	OS	Median	II,III,IV	0.298	0.484	.004	52	view →
LGG	OS	Median	All	0.872	0.742	<.001	48	view →
OV	DFS	Tertile	III,IV	0.213	0.140	.012	24	view →
SKCM	OS	Tertile	All	0.752	0.844	.009	19	view →
ESCA	DFS	Median	All	0.930	0.450	.003	15	view →
LUAD	OS	Quartile	All	0.344	0.630	.003	13	view →
THYM	DFS	Quartile	III,IV	0.222	1.000	.005	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

DUSP9–KIRC (OS)

Open the KIRC breakdown →