DUSP7

Across TCGA patient cohorts, DUSP7 mutation is significantly associated with the RNA expression of many other genes, with 127 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible DUSP7-associated genes across cancer lineages are RN7SL607P, SNORA70E, and RNU6-601P. Each is linked with DUSP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP7-to-partner and partner-to-DUSP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL607P grouped by DUSP7-low versus DUSP7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP7→partner) and Y-score (partner→DUSP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL607P →	+0.204	+5.575	<.001	.004	3	2
LUAD	SNORA70E →	+0.488	+5.217	.009	.007	3	2
UCEC	RNU6-601P →	+0.328	+3.997	<.001	.009	3	2
UCEC	FTH1P6 →	+0.321	+2.888	<.001	.008	3	2
UCEC	SUB1P2 →	+0.304	+3.233	.002	.002	3	2
BLCA	RPS12P24 →	+0.151	+4.883	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

RN7SL607P by DUSP7 expression — BRCA

Explore this box plot interactively →