DUSP6

Across TCGA patient cohorts, DUSP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,465 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUSP6-associated proteins across cancer lineages are PIK3C2A_S259, ZYX_S344, and SYNE2_S4136. Each is linked with DUSP6 in more than 7 cancer types. Because this analysis shows association rather than direction, both DUSP6-to-partner and partner-to-DUSP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP6 versus PIK3C2A_S259 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP6→partner) and Y-score (partner→DUSP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIK3C2A_S259 →	+0.556	+1.078	<.001	<.001	3	8
GBM	ZYX_S344 →	+0.481	+0.741	<.001	<.001	3	7
BRCA	SYNE2_S4136 →	+0.810	+1.152	<.001	<.001	3	7
UCEC	PHLDA1 →	+1.072	+0.847	<.001	<.001	3	6
BRCA	SPRY4_S125 →	+0.663	+1.329	.001	<.001	3	6
LUAD	NT5E →	+0.447	+0.633	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,465 associations by consensus.

DUSP6 vs PIK3C2A_S259 — BRCA

Explore this scatter interactively →