DUSP6

Across TCGA cell cohorts, DUSP6 RNA expression is significantly associated with the RNA expression of many other genes, with 8,606 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DUSP6-associated genes across cancer lineages are SPRY4, ETV5, and ETV4. Each is linked with DUSP6 in more than 15 cancer types. Because this analysis shows association rather than direction, both DUSP6-to-partner and partner-to-DUSP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP6 versus SPRY4 in BREAST, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP6→partner) and Y-score (partner→DUSP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SPRY4 →	+2.958	+3.908	<.001	<.001	3	16
BLOOD_Myeloma	ETV5 →	+3.022	+3.333	<.001	<.001	3	12
LIVER	ETV4 →	+2.996	+3.232	<.001	<.001	3	12
BLOOD_Lymphoma	SPRED1 →	+1.653	+2.629	<.001	<.001	3	11
BONE	GALNT4 →	+1.685	+2.421	.002	.003	1	12
LIVER	POC1B →	+1.255	+3.078	.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,606 associations by consensus.

DUSP6 vs SPRY4 — BREAST

Explore this scatter interactively →