DUSP3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,986 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DUSP3-associated genes across cancer lineages are COLEC12, LMOD1, and MSRB3. Each is linked with DUSP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both DUSP3-to-partner and partner-to-DUSP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP3 versus COLEC12 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP3→partner) and Y-score (partner→DUSP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCOLEC12 →+1.078+0.224<.001<.00137
UCECLMOD1 →+1.515+0.325<.001<.00137
UCECMSRB3 →+1.235+0.298<.001<.00137
OVPLN →+1.532+0.464<.001<.00137
GBMMS4A4E →+1.033+0.221.001<.00137
OVMAGI2-AS3 →+0.797+0.298<.001.00237
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,986 associations by consensus.

DUSP3 vs COLEC12 — GBM

Per-sample scatter of DUSP3 vs COLEC12 in GBM (Pearson r = 0.49).

Explore this scatter interactively →

Exploration