DUSP23

Across TCGA pan-cancer cohorts, DUSP23 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DUSP23 data layer compared with 25 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DUSP23 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DUSP23 expression acts as an unfavorable survival marker.

COAD, UCEC, and LUSC are the cancer types where DUSP23 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.111	0.871	<.001	24	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUSC	DFS	Median	All	0.165	0.707	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DUSP23–COAD (OS)

Open the COAD breakdown →