DUSP23

Across TCGA cell cohorts, DUSP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,369 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DUSP23-associated GO terms across cancer lineages are Endosomal transport, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Cellular respiration. Each is linked with DUSP23 in more than 8 cancer types. Because this analysis shows association rather than direction, both DUSP23-to-partner and partner-to-DUSP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by DUSP23-low versus DUSP23-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP23→partner) and Y-score (partner→DUSP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.029	+0.932	.005	.003	3	8
BREAST	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.203	+1.523	<.001	.001	3	8
LUNG_NSCLC_LUAD	Cellular respiration →	+0.066	+1.261	<.001	.001	2	9
UPPER_AERODIGESTIVE_TRACT	Oxidative phosphorylation →	+0.084	+1.806	.002	.002	3	8
SOFT_TISSUE	ATP metabolic process →	+0.063	+2.348	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.084	+1.771	.002	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

Endosomal transport by DUSP23 expression — SKIN

Explore this box plot interactively →