DUSP22

Across TCGA patient cohorts, DUSP22 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DUSP22-associated proteins across cancer lineages are PTDSS1_S442, KPNA2, and PDLIM4. Each is linked with DUSP22 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUSP22-to-partner and partner-to-DUSP22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP22 versus PTDSS1_S442 in GBM, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP22→partner) and Y-score (partner→DUSP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTDSS1_S442 →	-0.657	-0.423	<.001	<.001	3	4
GBM	KPNA2 →	-0.463	-0.454	<.001	<.001	3	4
CCRCC	PDLIM4 →	+0.777	+0.279	<.001	.001	3	4
BRCA	NME1 →	-0.643	-0.569	<.001	<.001	3	4
GBM	OSTF1 →	+0.396	+0.281	<.001	.002	3	4
OV	RIPK1 →	+0.320	+0.595	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,762 associations by consensus.

DUSP22 vs PTDSS1_S442 — GBM

Explore this scatter interactively →