DUSP22

Across TCGA patient cohorts, DUSP22 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP22-associated genes across cancer lineages are Osteoblast, Endothelial cells, and lymphatic Endothelial cells. Each is linked with DUSP22 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP22-to-partner and partner-to-DUSP22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by DUSP22-low versus DUSP22-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP22→partner) and Y-score (partner→DUSP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Osteoblast →	+0.042	+3.494	.003	.030	3	2
UCEC	Endothelial cells →	-0.035	-2.451	.020	.020	3	1
UCEC	lymphatic Endothelial cells →	-0.020	-3.138	.035	.019	3	1
UCEC	Preadipocytes →	-0.037	-2.095	.043	.044	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Osteoblast by DUSP22 expression — LUAD

Explore this box plot interactively →