Across TCGA patient cohorts, DUSP21 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,454 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DUSP21-associated GO terms across cancer lineages are Negative regulation of DNA metabolic process, Negative regulation of transferase activity, and Protein K48-linked ubiquitination. Each is linked with DUSP21 in more than 9 cancer types. Because this analysis shows association rather than direction, both DUSP21-to-partner and partner-to-DUSP21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP21→partner) and Y-score (partner→DUSP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of DNA metabolic process →	+0.060	+0.085	<.001	.002	3	9
ESCA	Negative regulation of transferase activity →	+0.057	+0.084	<.001	.003	3	9
STAD	Protein K48-linked ubiquitination →	+0.068	+0.093	<.001	<.001	3	9
STAD	Glycosyl compound metabolic process →	+0.044	+0.123	<.001	<.001	3	9
ESCA	Protein export from nucleus →	+0.060	+0.083	<.001	.003	2	10
STAD	Endosome organization →	+0.061	+0.093	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,454 associations by consensus.

Exploration

DUSP21 survival (RNA) · tumor vs normal (RNA) · all DUSP21 data types