Across TCGA cell cohorts, DUSP21 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DUSP21-associated genes across cancer lineages are SPINK9, MDFIC2, and OR10G4. Each is linked with DUSP21 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP21-to-partner and partner-to-DUSP21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP21→partner) and Y-score (partner→DUSP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SPINK9 →	+0.065	+5.415	<.001	.004	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1
SKIN	OR10G4 →	+0.006	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR10G2 →	+0.074	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

DUSP21 survival (RNA) · tumor vs normal (RNA) · all DUSP21 data types