DUSP18

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DUSP18 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated DUSP18 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher DUSP18 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DUSP18 expression acts as an unfavorable survival marker.

LIHC and BLCA are the cancer types where DUSP18 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSMedianAll0.1440.688.0139view →
BLCADFSMedianAll0.1530.615.0246view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DUSP18–LIHC (OS)

Kaplan–Meier survival curve for DUSP18 mutant vs wild-type samples in LIHC.

Open the LIHC breakdown →

Exploration