DUSP18

Across TCGA patient cohorts, DUSP18 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,915 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUSP18-associated proteins across cancer lineages are TBC1D22A, IFT27, and MAPK1. Each is linked with DUSP18 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUSP18-to-partner and partner-to-DUSP18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUSP18 versus TBC1D22A in GBM, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP18→partner) and Y-score (partner→DUSP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TBC1D22A →	+0.189	+0.303	.008	.001	3	4
BRCA	IFT27 →	+0.496	+0.424	<.001	<.001	3	4
BRCA	MAPK1 →	+0.188	+0.431	<.001	<.001	3	4
BRCA	BBS2 →	+0.581	+0.434	<.001	<.001	3	4
BRCA	PICK1 →	+0.390	+0.403	.002	.001	3	3
BRCA	RPSA →	-0.238	-0.393	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,915 associations by consensus.

DUSP18 vs TBC1D22A — GBM

Explore this scatter interactively →