DUSP18

Across TCGA cell cohorts, DUSP18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,379 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DUSP18-associated GO terms across cancer lineages are Cytosolic transport, Vesicle cytoskeletal trafficking, and Retrograde transport, endosome to Golgi. Each is linked with DUSP18 in more than 16 cancer types. Because this analysis shows association rather than direction, both DUSP18-to-partner and partner-to-DUSP18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by DUSP18-low versus DUSP18-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP18→partner) and Y-score (partner→DUSP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.085	+1.001	<.001	<.001	3	17
LIVER	Vesicle cytoskeletal trafficking →	+0.094	+1.173	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.083	+1.184	<.001	<.001	3	15
BLOOD_Myeloma	Cytoskeleton-dependent intracellular transport →	+0.038	+1.095	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.236	+1.144	.001	<.001	3	15
SKIN	Endosomal transport →	+0.072	+0.747	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,379 associations by consensus.

Cytosolic transport by DUSP18 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →