DUSP15

Across TCGA patient cohorts, DUSP15 mutation is significantly associated with the RNA expression of many other genes, with 660 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DUSP15-associated genes across cancer lineages are RN7SL483P, OFD1P2Y, and MIR6075. Each is linked with DUSP15 in more than 2 cancer types. Because this analysis shows association rather than direction, both DUSP15-to-partner and partner-to-DUSP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL483P grouped by DUSP15-low versus DUSP15-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP15→partner) and Y-score (partner→DUSP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL483P →	+0.268	+5.273	<.001	.006	3	3
COAD	OFD1P2Y →	+0.059	+6.409	<.001	<.001	3	2
COAD	MIR6075 →	+0.620	+4.717	<.001	.003	3	2
LUAD	USP8P2 →	+0.238	+4.303	.001	.001	3	2
LUAD	EIF4BP4 →	+0.030	+3.415	<.001	.009	3	2
LUAD	HMGB3P26 →	+0.120	+4.137	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 660 associations by consensus.

RN7SL483P by DUSP15 expression — LUSC

Explore this box plot interactively →