Q-omics provides the consensus-scored USP8P2 profile across patient tissues and cancer cell-line models. USP8P2 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, USP8P2 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, USP8P2 RNA expression shows 7,310 significant gene co-expression associations, with the highest sampling consensus in GBM. Together, these results highlight UVM, COAD, and GBM as cancer lineages where USP8P2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for USP8P2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes USP8P2 survival associations across molecular data types. USP8P2 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible USP8P2 RNA expression–survival associations across cancer types. High USP8P2 expression shows unfavorable associations in UVM, LGG and CHOL, but favorable associations in KIRC, TGCT and THCA. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify UVM as the clearest survival context for USP8P2 RNA expression.
This table summarizes USP8P2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for USP8P2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. USP8P2 shows lower tumor expression in COAD and higher tumor expression in THCA, PRAD, KIRC and LIHC. The COAD box plot shows higher USP8P2 RNA expression in normal versus tumor tissue (log2 FC = −0.084, t-test p = .012).
This table shows molecular features associated with USP8P2 in patient tissues and cancer cell lines. In patient samples, USP8P2 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
