DUSP12

Across TCGA pan-cancer cohorts, DUSP12 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DUSP12 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DUSP12 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DUSP12 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and CCRCC are the cancer types where DUSP12 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	III,IV	0.875	0.214	.006	10	view →
UCEC	DFS	Median	All	1.000	0.941	.038	6	view →
CCRCC	OS	Quartile	All	0.731	0.926	.034	4	view →
LSCC	DFS	Median	All	0.970	0.910	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DUSP12–PDAC (DFS)

Open the PDAC breakdown →