DUSP12

Across TCGA patient cohorts, DUSP12 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP12-associated genes across cancer lineages are mv Endothelial cells, pDC, and Th2 cells. Each is linked with DUSP12 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP12-to-partner and partner-to-DUSP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by DUSP12-low versus DUSP12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP12→partner) and Y-score (partner→DUSP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mv Endothelial cells →	-0.030	-3.000	.022	.036	3	1
UCEC	pDC →	+0.058	+2.815	.029	.036	3	1
UCEC	Th2 cells →	+0.246	+3.169	.013	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

mv Endothelial cells by DUSP12 expression — UCEC

Explore this box plot interactively →