DUSP10

Across TCGA cell cohorts, DUSP10 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DUSP10-associated genes across cancer lineages are OR1L3, FAM47C, and ZNF831. Each is linked with DUSP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP10-to-partner and partner-to-DUSP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by DUSP10-low versus DUSP10-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP10→partner) and Y-score (partner→DUSP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.227	+4.095	<.001	.009	3	1
LARGE_INTESTINE	DEFA3 →	+0.076	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR1L3 by DUSP10 expression — SKIN

Explore this box plot interactively →