DUS2

Across TCGA cell cohorts, DUS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,512 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DUS2-associated GO terms across cancer lineages are Mitochondrial ribosome assembly, Mitochondrial large ribosomal subunit assembly, and 'de novo' UMP biosynthetic process. Each is linked with DUS2 in more than 13 cancer types. Because this analysis shows association rather than direction, both DUS2-to-partner and partner-to-DUS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial ribosome assembly grouped by DUS2-low versus DUS2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUS2→partner) and Y-score (partner→DUS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.103	+0.890	<.001	<.001	3	14
BLOOD_Myeloma	Mitochondrial large ribosomal subunit assembly →	+0.142	+1.013	.001	.002	2	13
LUNG_NSCLC_LUSC	'de novo' UMP biosynthetic process →	+0.152	+0.925	<.001	.001	3	12
KIDNEY	Basophil activation →	+0.160	+0.643	<.001	.003	3	12
LUNG_SCLC	Glycine betaine transport →	+0.192	+0.617	<.001	<.001	3	11
BREAST	Protection from non-homologous end joining at telomere →	+0.116	+0.930	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,512 associations by consensus.

Mitochondrial ribosome assembly by DUS2 expression — BLOOD_Lymphoma

Explore this box plot interactively →