DUOXA2

Across TCGA patient cohorts, DUOXA2 protein abundance is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DUOXA2-associated genes across cancer lineages are OLFM4, FBXO31, and OGDH. Each is linked with DUOXA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUOXA2-to-partner and partner-to-DUOXA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA2 versus OLFM4 in PDAC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA2→partner) and Y-score (partner→DUOXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	OLFM4 →	+2.522	+0.839	.008	.009	3	1
PDAC	FBXO31 →	-0.226	-0.764	.005	.001	3	1
PDAC	OGDH →	-0.272	-0.898	.003	<.001	3	1
PDAC	MEST →	-0.518	-1.151	.005	<.001	3	1
PDAC	ANKMY2 →	-0.267	-0.638	.002	.002	3	1
PDAC	GATA3 →	-0.943	-1.108	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

DUOXA2 vs OLFM4 — PDAC

Explore this scatter interactively →