DUOXA1

Across TCGA patient cohorts, DUOXA1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,825 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DUOXA1-associated genes across cancer lineages are GCOM1, SUZ12P1, and NDUFAF7. Each is linked with DUOXA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DUOXA1-to-partner and partner-to-DUOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA1 versus GCOM1 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA1→partner) and Y-score (partner→DUOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GCOM1 →	+0.790	+0.634	<.001	<.001	3	3
HNSC	SUZ12P1 →	-0.610	-0.722	<.001	<.001	3	3
HNSC	NDUFAF7 →	-0.720	-0.703	<.001	<.001	3	3
UCEC	CLU →	-3.186	-1.924	<.001	.003	3	2
UCEC	PGBD1 →	-0.903	-2.170	.001	.007	3	2
UCEC	MIR760 →	-1.886	-1.679	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,825 associations by consensus.

DUOXA1 vs GCOM1 — HNSC

Explore this scatter interactively →