DUOXA1

Across TCGA patient cohorts, DUOXA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,098 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DUOXA1-associated proteins across cancer lineages are DUOX1, DUOX1_S634, and SF3B2. Each is linked with DUOXA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DUOXA1-to-partner and partner-to-DUOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA1 versus DUOX1 in HNSC, with a Pearson correlation of 0.87.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA1→partner) and Y-score (partner→DUOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DUOX1 →	+0.776	+1.102	<.001	<.001	3	3
HNSC	DUOX1_S634 →	+1.453	+1.129	<.001	<.001	3	3
HNSC	SF3B2 →	-0.174	-0.738	<.001	<.001	3	3
LUAD	DUOXA1_S313 →	+1.052	+0.455	<.001	.002	3	3
LUAD	KAZN_S346 →	+0.887	+0.598	<.001	<.001	3	3
HNSC	KIF1C →	+0.303	+0.751	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,098 associations by consensus.

DUOXA1 vs DUOX1 — HNSC

Explore this scatter interactively →