DUBR

Across TCGA patient cohorts, DUBR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,068 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUBR-associated proteins across cancer lineages are YME1L1, USP15_S229, and CLPX. Each is linked with DUBR in more than 6 cancer types. Because this analysis shows association rather than direction, both DUBR-to-partner and partner-to-DUBR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUBR versus YME1L1 in HNSC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUBR→partner) and Y-score (partner→DUBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	YME1L1 →	-0.294	-0.702	<.001	<.001	3	7
LUAD	USP15_S229 →	-0.679	-0.582	<.001	<.001	3	6
LUAD	CLPX →	-0.295	-0.318	<.001	<.001	3	6
BRCA	MMP2 →	+0.731	+0.531	<.001	.001	3	6
UCEC	AGO1 →	+0.291	+0.664	<.001	<.001	3	6
COAD	FHL3 →	+0.588	+0.319	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,068 associations by consensus.

DUBR vs YME1L1 — HNSC

Explore this scatter interactively →