DTYMK

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DTYMK RNA expression is significantly associated with the protein abundance of many other proteins, with 19,211 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTYMK-associated proteins across cancer lineages are MCM2, MCM3, and MCM4. Each is linked with DTYMK in more than 9 cancer types. Because this analysis shows association rather than direction, both DTYMK-to-partner and partner-to-DTYMK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTYMK versus MCM2 in GBM, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTYMK→partner) and Y-score (partner→DTYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMCM2 →+0.802+0.562<.001<.001310
GBMMCM3 →+0.815+0.560<.001<.001310
GBMMCM4 →+0.829+0.548<.001<.001310
GBMMCM5 →+0.844+0.575<.001<.001310
GBMMCM6 →+0.914+0.564<.001<.001310
GBMMCM7 →+0.812+0.554<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,211 associations by consensus.

DTYMK vs MCM2 — GBM

Per-sample scatter of DTYMK vs MCM2 in GBM (Pearson r = 0.76).

Explore this scatter interactively →

Exploration