DTX4

Across TCGA patient cohorts, DTX4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,223 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTX4-associated genes across cancer lineages are PRORP, PSMA6, and DNAJC3. Each is linked with DTX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTX4-to-partner and partner-to-DTX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX4 versus PRORP in LUAD, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX4→partner) and Y-score (partner→DTX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRORP →	-0.730	-0.965	<.001	.002	3	1
LUAD	PSMA6 →	-0.666	-0.781	.002	.009	3	1
LUAD	DNAJC3 →	+0.509	+0.752	.003	.003	3	1
LUAD	GYS1 →	-0.515	-1.049	.002	.003	3	1
LUAD	LIN7B →	-0.505	-1.137	<.001	.002	3	1
LUAD	SF3A2 →	-0.518	-0.794	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,223 associations by consensus.

DTX4 vs PRORP — LUAD

Explore this scatter interactively →