DTX4

Across TCGA cell cohorts, DTX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,048 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DTX4-associated GO terms across cancer lineages are Protein localization to cell junction, Bundle of His cell-Purkinje myocyte adhesion involved in cell communication, and RNA stabilization. Each is linked with DTX4 in more than 10 cancer types. Because this analysis shows association rather than direction, both DTX4-to-partner and partner-to-DTX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cell junction grouped by DTX4-low versus DTX4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX4→partner) and Y-score (partner→DTX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to cell junction →	+0.123	+2.010	<.001	<.001	3	11
BLOOD_Lymphoma	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+0.928	+1.441	.001	<.001	3	11
SOFT_TISSUE	RNA stabilization →	+0.085	+1.848	<.001	<.001	3	11
STOMACH	Regulation of response to type II interferon →	+0.199	+1.779	<.001	<.001	3	10
STOMACH	Regulation of type II interferon-mediated signaling pathway →	+0.199	+1.779	<.001	<.001	3	10
URINARY_TRACT	Signal complex assembly →	+0.214	+3.964	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,048 associations by consensus.

Protein localization to cell junction by DTX4 expression — OESOPHAGUS

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